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Top Non-Surgical Approaches for Peyronie’s Disease Relief

May 30, 2025

A Specialist doctor is diagnosing a male patient with symptoms of Peyronie’s disease and providing health counselling.

If you are exploring non-surgical treatment for Peyronie’s disease, you are not alone. Many men seek effective and less invasive options to manage this condition, which can cause curvature of the penis, pain, and difficulties with sexual function.

Fortunately, several non-surgical approaches can provide relief and even improve symptoms.

Let us discuss the top non-surgical treatments available for Peyronie’s disease and explain how they work. From intralesional injections to traction devices, these approaches offer alternatives to surgery that focus on minimizing pain and enhancing quality of life.

Understanding Peyronie’s Disease

Peyronie’s disease occurs when plaque (fibrous scar tissue) develops under the skin of the penis. This can result in a noticeable bend or curve during an erection.

For some men, the curvature is mild, while others experience pain, difficulty during intercourse, or overall emotional distress. Thankfully, advances in non-surgical treatments provide solutions that can alleviate symptoms and potentially reduce the curvature without the risks of surgery.

Top Non-Surgical Treatments for Peyronie’s Disease

Here are the best non-surgical approaches to treating this condition.

1.     Intralesional Injection Therapy

Intralesional injection therapy involves injecting medication directly into the plaque to break down the fibrous tissue causing the curvature.

Two widely used medications include:

  • Xiaflex® is the first FDA-approved treatment specifically for Peyronie’s disease. It works by breaking down collagen in the scar tissue, reducing curvature over time. This treatment is typically used in combination with manual techniques like penile stretching or modeling exercises prescribed by your healthcare provider.
  • Verapamil is another option commonly used off-label. Verapamil helps disrupt collagen production and promotes tissue repair, potentially softening the plaque and reducing discomfort.

This therapy is performed in a doctor’s office over a series of sessions and is most effective during the early stages of Peyronie’s disease.

2.     Oral Medications

Certain oral medications can be part of a non-surgical treatment plan, although their effectiveness varies based on the severity of the disease.

Common oral therapies include:

  • Pentoxifylline: This medication is often prescribed to improve blood flow and decrease inflammation. It may help reduce plaque formation and improve penile curvature when used in the early stages.
  • Vitamin E and Other Antioxidants: These supplements can help reduce oxidative stress in the penile tissues, contributing to scar tissue formation. However, current studies show mixed results regarding their efficacy.

While oral medications are less invasive and easier to administer, they are most beneficial when combined with other treatments, such as injection therapy or mechanical devices.

3.     Vacuum Erection Devices

Vacuum erection devices (VEDs) create a vacuum around the penis, increasing blood flow and improving erectile function.

For Peyronie’s disease, VEDs can be used as a form of mechanical therapy to stretch the scar tissue and reduce curvature. Over time, consistent use of a VED may improve penile length and curvature while aiding in maintaining overall penile health.

VEDs should only be used under a physician’s guidance, as improper use can worsen symptoms or cause damage. It is best to discuss this option with your doctor to ensure proper technique and usage.

4.     Traction Devices

Traction devices are another promising non-surgical treatment for Peyronie’s disease.

These devices use gentle, consistent stretching to improve penile curvature and length. Traction therapy works by slowly remodeling the fibrous scar tissue, promoting a more natural alignment of the penis.

Studies show that traction devices can work alone or as an adjunct to other treatments, like injections or surgery. For the best results, patients need to use these devices consistently over several months.

Although this approach requires dedication, it has been shown to improve both curvature and overall satisfaction.

Why Choose Dr. Desiderio Avila, Jr. at Ironwood Urology

Selecting the right healthcare provider is crucial when seeking treatment for Peyronie’s disease. Dr. Desiderio Avila, Jr., at Ironwood Urology, is a leading urologist specializing in men’s health with extensive experience in treating Peyronie’s disease using non-surgical and surgical options.

Here are just a few reasons why patients choose his care:

  • Expertise in Non-Surgical Solutions: Dr. Avila specializes in the latest non-surgical therapies, leaving invasive surgical options to the last resort.
  • Comprehensive and Personalized Treatment: Every treatment plan is developed with your specific health needs in mind, focusing on effective symptom management and lasting results.
  • Trusted Track Record: With years of experience and a proven history of helping men overcome Peyronie’s disease, Dr. Avila has become a trusted provider in urological care.

By choosing Dr. Avila and the team at Ironwood Urology, you are not only gaining access to cutting-edge treatments but also a compassionate approach to care that aims for your overall well-being.

Non-Surgical Care for Peyronie’s Disease in Phoenix & Gilbert, AZ

For those seeking expert guidance, Dr. Desiderio Avila, Jr. at Ironwood Urology offers specialized care and a commitment to improving your quality of life. He works with each patient on an individual basis to ensure they receive the highest quality care for their condition, all while avoiding invasive surgical procedures.

If you are ready to explore non-surgical treatment options for Peyronie’s disease, do not hesitate to schedule a consultation today. Call Dr. Avila at (480) 961-2323 to use our appointment request form.

We look forward to helping you regain your comfort and confidence!

 

Filed Under: Peyronie's Disease Tagged With: best non-surgical approaches, Intralesional injection therapy, non surgical treatment for peyronie's disease, Non-Surgical Care for Peyronie’s Disease in Phoenix & Gilbert, Oral Medications, Peyronie's Disease, Peyronie's disease treatment, Traction devices, Traction therapy, Vacuum Erection Devices

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Dr. Avila focuses on all aspects of men's health, including vasectomy, vasectomy reversal, male infertility, low testosterone, erectile dysfunction, penile prosthetic surgery, Peyronie’s disease, prostate health, and robotic urological surgery.